Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Fancmtm1.1Htr
Name:	Fanconi anemia, complementation group M; targeted mutation 1.1, Hein Te Riele
MGI ID:	MGI:4355560
Synonyms:	Fancmdelta2
Gene:	Fancm  Location: Chr12:65122377-65178832 bp, + strand  Genetic Position: Chr12, 27.21 cM
Alliance:	Fancmtm1.1Htr page

Germline Transmission:	Earliest citation of germline transmission: J:151714
Parent Cell Line:	Bruce 4 (ES Cell)
Strain of Origin:	B6.Cg-Thy1a

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Germ line, cre mediated recombination removed exon 2 and the neo cassette. The absence of protein expression was confirmed by western blot analysis on mouse embryonic fibroblast extracts. (J:151714)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fancm Mutation:	119 strains or lines available

Original:	J:151714 Bakker ST, et al., Fancm-deficient mice reveal unique features of Fanconi anemia complementation group M. Hum Mol Genet. 2009 Sep 15;18(18):3484-95
All:	1 reference(s)