Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nqo1tm1Msho
Name:	NAD(P)H dehydrogenase, quinone 1; targeted mutation 1, Minho Shong
MGI ID:	MGI:4353051
Gene:	Nqo1  Location: Chr8:108114857-108129838 bp, - strand  Genetic Position: Chr8, 54.08 cM
Alliance:	Nqo1tm1Msho page

Germline Transmission:	Earliest citation of germline transmission: J:151045
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A 3425 bp fragment including exons 5 and 6 was replaced with a pgk-neo cassette via homologous recombination. (J:151045)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nqo1 Mutation:	24 strains or lines available

Original:	J:151045 Hwang JH, et al., Pharmacological stimulation of NADH oxidation ameliorates obesity and related phenotypes in mice. Diabetes. 2009 Apr;58(4):965-74
All:	5 reference(s)