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Zbtb18tm1Haok
Targeted Allele Detail
Summary
Symbol: Zbtb18tm1Haok
Name: zinc finger and BTB domain containing 18; targeted mutation 1, Haruo Okado
MGI ID: MGI:3851929
Synonyms: RP58-
Gene: Zbtb18  Location: Chr1:177269917-177278330 bp, + strand  Genetic Position: Chr1, 82.72 cM, cytoband H3
Alliance: Zbtb18tm1Haok page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:150768
Parent Cell Line:  GS1 (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on embryonic brain extracts. (J:150768)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 18 assay results
2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 8 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Zbtb18 Mutation:  26 strains or lines available
References
Original:  J:150768 Okado H, et al., The transcriptional repressor RP58 is crucial for cell-division patterning and neuronal survival in the developing cortex. Dev Biol. 2009 Jul 15;331(2):140-51
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory