Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Aifm1tm2.1Pngr
Name:	apoptosis-inducing factor, mitochondrion-associated 1; targeted mutation 2.1, Josef M Penninger
MGI ID:	MGI:3851178
Synonyms:	Aifdeltaex7
Gene:	Aifm1  Location: ChrX:47563821-47602440 bp, - strand  Genetic Position: ChrX, 25.68 cM, cytoband A6
Alliance:	Aifm1tm2.1Pngr page

Germline Transmission:	Earliest citation of germline transmission: J:111066
Parent Cell Line:	E14TG2a.4 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     Germ line, cre mediated recombination removes exon 7. (J:111066)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	7 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Aifm1 Mutation:	10 strains or lines available

Original:	J:111066 Brown D, et al., Loss of Aif function causes cell death in the mouse embryo, but the temporal progression of patterning is normal. Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9918-23
All:	1 reference(s)