Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Grin2ctm2Rsp
Name:	glutamate receptor, ionotropic, NMDA2C (epsilon 3); targeted mutation 2, Rolf Sprengel
MGI ID:	MGI:3850683
Synonyms:	NR2C-
Gene:	Grin2c  Location: Chr11:115139995-115158069 bp, - strand  Genetic Position: Chr11, 80.8 cM
Alliance:	Grin2ctm2Rsp page

Germline Transmission:	Earliest citation of germline transmission: J:45446
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     A neomycin selection cassette replaced a part of intron 4 and exon 5. (J:45446) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Grin2c Mutation:	56 strains or lines available

Original:	J:45446 Sprengel R, et al., Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo. Cell. 1998 Jan 23;92(2):279-89
All:	3 reference(s)