Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Clrn1tm1.1Kuna
Name:	clarin 1; targeted mutation 1.1, Kumar N Alagramam
MGI ID:	MGI:3850171
Gene:	Clrn1  Location: Chr3:58751449-58792633 bp, - strand  Genetic Position: Chr3, 28.78 cM
Alliance:	Clrn1tm1.1Kuna page

Germline Transmission:	Earliest citation of germline transmission: J:150215
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6J

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Germ line, cre mediated recombination removes the neo cassette and exon 1. RT-PCR on P30 and P60 cochlear extracts confirmed the absence of transcript expression. (J:150215)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Clrn1 Mutation:	16 strains or lines available

Original:	J:150215 Geng R, et al., Usher syndrome IIIA gene clarin-1 is essential for hair cell function and associated neural activation. Hum Mol Genet. 2009 Aug 1;18(15):2748-60
All:	10 reference(s)