Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Sun2tm1Mhan
Name:	Sad1 and UNC84 domain containing 2; targeted mutation 1, Min Han
MGI ID:	MGI:3850087
Synonyms:	Sun2-
Gene:	Sun2  Location: Chr15:79608271-79626737 bp, - strand  Genetic Position: Chr15, 37.85 cM
Alliance:	Sun2tm1Mhan page

Germline Transmission:	Earliest citation of germline transmission: J:150047
Parent Cell Line:	W4 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 11 through 16 were replaced with a neo cassette. The absence of protein expression was confirmed by immunohistochemistry on muscle fiber samples. (J:150047)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

27 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sun2 Mutation:	42 strains or lines available

Original:	J:150047 Lei K, et al., SUN1 and SUN2 play critical but partially redundant roles in anchoring nuclei in skeletal muscle cells in mice. Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10207-12
All:	12 reference(s)