Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Prdx4tm1.1Jufu
Name:	peroxiredoxin 4; targeted mutation 1.1, Junichi Fujii
MGI ID:	MGI:3848347
Synonyms:	Prx4-
Gene:	Prdx4  Location: ChrX:154106914-154123750 bp, - strand  Genetic Position: ChrX, 72.38 cM
Alliance:	Prdx4tm1.1Jufu page

Germline Transmission:	Earliest citation of germline transmission: J:149074
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Germ line, cre mediated recombination removed exon 1. The absence of protein expression was confirmed by western blot analysis on pancreas, spleen, kidney, large intestine, and testis of male mice. (J:149074)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	27 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prdx4 Mutation:	9 strains or lines available

Original:	J:149074 Iuchi Y, et al., Peroxiredoxin 4 knockout results in elevated spermatogenic cell death via oxidative stress. Biochem J. 2009 Apr 1;419(1):149-58
All:	8 reference(s)