Pidd1tm1.1Anvi
Targeted Allele Detail
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| Symbol: |
Pidd1tm1.1Anvi |
| Name: |
p53 induced death domain protein 1; targeted mutation 1.1, Andreas Villunger |
| MGI ID: |
MGI:3847893 |
| Synonyms: |
pidd- |
| Gene: |
Pidd1 Location: Chr7:141018026-141023938 bp, - strand Genetic Position: Chr7, 86.79 cM
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| Alliance: |
Pidd1tm1.1Anvi page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:148929
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Exons 3-15 of the gene were replaced by the open reading frame of beta-galactosidase followed by a loxP flanked neo cassette. The loxP flanked neo cassette was removed in vivo by cre-mediated deletion. RT-PCR analysis confirmed the absence of mRNA in thymocytes and MEFs. Absence of protein product was confirmed by western blot of thymocyte extracts derived from homozygous mice.
(J:148929)
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Generation of the Pidd1tm1.1Anvi allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Pidd1 Mutation: |
52 strains or lines available
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| Original: |
J:148929 Manzl C, et al., Caspase-2 activation in the absence of PIDDosome formation. J Cell Biol. 2009 Apr 20;185(2):291-303 |
| All: |
7 reference(s) |
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Analysis Tools
