Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Cavin3tm1(KOMP)Vlcg
Name:	caveolae associated 3; targeted mutation 1, Velocigene
MGI ID:	MGI:3847505
Gene:	Cavin3  Location: Chr7:105129823-105131404 bp, - strand  Genetic Position: Chr7, 55.87 cM, cytoband F1
Alliance:	Cavin3tm1(KOMP)Vlcg page
IMPC:	Cavin3 gene page

Mutant Cell Lines:	11448A-A5, 11448A-A12, 11448A-C3, 11448A-C6, 11448A-D8
Germline Transmission:	Earliest citation of germline transmission: J:205741
Parent Cell Line:	VGB6 (ES Cell)
Strain of Origin:	C57BL/6NTac
Project Collection:	KOMP-Regeneron

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion     Vector: ZEN-Ub1   Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 1369bp between positions 105129995-105131363 of Chromosome 7 (Build GRCm39). The cassette replaced exon 1. Western blot analysis confirmed the absence of protein expression in the lung, heart, fat, skeletal muscle, brain and liver. (J:136110, J:205741)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 1 line available
Carrying any Cavin3 Mutation:	11 strains or lines available

Original:	J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008;
All:	4 reference(s)