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Klf13tm1Kren
Targeted Allele Detail
Summary
Symbol: Klf13tm1Kren
Name: Kruppel-like transcription factor 13; targeted mutation 1, Alan M Krensky
MGI ID: MGI:3839530
Gene: Klf13  Location: Chr7:63536099-63588663 bp, - strand  Genetic Position: Chr7, 34.58 cM
Alliance: Klf13tm1Kren page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:145839
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 was replaced with a neomycin selection cassette. PCR analysis could not detect any mRNA in homozygous mice and Western blot analysis did not detect any protein in either thymocytes or splenocytes. (J:145839)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Klf13 Mutation:  47 strains or lines available
References
Original:  J:145839 Zhou M, et al., Kruppel-like transcription factor 13 regulates T lymphocyte survival in vivo. J Immunol. 2007 May 1;178(9):5496-504
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory