Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gper1tm1135.2Arte
Name:	G protein-coupled estrogen receptor 1; targeted mutation 1135.2, TaconicArtemis
MGI ID:	MGI:3839350
Gene:	Gper1  Location: Chr5:139408906-139413555 bp, + strand  Genetic Position: Chr5, 78.58 cM, cytoband G1
Alliance:	Gper1tm1135.2Arte page

Germline Transmission:	Earliest citation of germline transmission: J:145794
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6N

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Germ line, cre mediated recombination was used to remove exon 3 and the neo cassette. The absence of transcript expression was confirmed by quantitative RT-PCR on stomach, ovary, mammary gland, and uterus extracts. (J:145794)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gper1 Mutation:	27 strains or lines available

Original:	J:145794 Otto C, et al., GPR30 does not mediate estrogenic responses in reproductive organs in mice. Biol Reprod. 2009 Jan;80(1):34-41
All:	2 reference(s)