Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pink1tm1Zhzh
Name:	PTEN induced putative kinase 1; targeted mutation 1, Zhuohua Zhang
MGI ID:	MGI:3837552
Gene:	Pink1  Location: Chr4:138040720-138053618 bp, - strand  Genetic Position: Chr4, 70.14 cM
Alliance:	Pink1tm1Zhzh page

Germline Transmission:	Earliest citation of germline transmission: J:146282
Parent Cell Line:	E14TG2a.4 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 4 through 7 were replaced with an frt flanked neo cassette. The absence of transcript expression was confirmed by RT-PCR and in situ hybridization. (J:146282)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pink1 Mutation:	42 strains or lines available

Original:	J:146282 Xiong H, et al., Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation. J Clin Invest. 2009 Mar;119(3):650-60
All:	11 reference(s)