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Cngb1tm1Hazh
Targeted Allele Detail
Summary
Symbol: Cngb1tm1Hazh
Name: cyclic nucleotide gated channel beta 1; targeted mutation 1, Haiqing Zhao
MGI ID: MGI:3834618
Synonyms: CNBG1deltaCaM
Gene: Cngb1  Location: Chr8:95965673-96033213 bp, - strand  Genetic Position: Chr8, 47.12 cM
Alliance: Cngb1tm1Hazh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:145296
Parent Cell Line:  MC1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe sequence encoding the 20 amino acids of the calmodulin binding domain was removed, and a floxed neo cassette used for selection was removed by germ line, cre mediated recombination. (J:145296)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cngb1 Mutation:  61 strains or lines available
References
Original:  J:145296 Song Y, et al., Olfactory CNG channel desensitization by Ca2+/CaM via the B1b subunit affects response termination but not sensitivity to recurring stimulation. Neuron. 2008 May 8;58(3):374-86
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory