Itprid2tm1Sawa
Targeted Allele Detail
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Symbol: |
Itprid2tm1Sawa |
Name: |
ITPR interacting domain containing 2; targeted mutation 1, Senji Shirasawa |
MGI ID: |
MGI:3833897 |
Synonyms: |
KRAP- |
Gene: |
Itprid2 Location: Chr2:79465696-79503310 bp, + strand Genetic Position: Chr2, 47.58 cM, cytoband D
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Alliance: |
Itprid2tm1Sawa page
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Resistance to fatty liver formation in Itprid2tm1Sawa/Itprid2tm1Sawa mice
Show the 2 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:144968
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Exons 11 - 16, encompassing 55% of the coding region of the gene, were replaced with a neo cassette via homologous recombination. Western blot analysis confirmed the absence of protein expression in livers from homozygous mice.
(J:144968)
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Generation of the Itprid2tm1Sawa allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Itprid2 Mutation: |
48 strains or lines available
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Original: |
J:144968 Fujimoto T, et al., Altered energy homeostasis and resistance to diet-induced obesity in KRAP-deficient mice. PLoS One. 2009;4(1):e4240 |
All: |
2 reference(s) |
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