Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gpr83tm1.1Fpow
Name:	G protein-coupled receptor 83; targeted mutation 1.1, Fiona Powrie
MGI ID:	MGI:3831302
Gene:	Gpr83  Location: Chr9:14771506-14782085 bp, + strand  Genetic Position: Chr9, 4.4 cM, cytoband A2-A3
Alliance:	Gpr83tm1.1Fpow page

Germline Transmission:	Earliest citation of germline transmission: J:144445
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Germ line, cre-mediated recombination was used to remove exons 2 and 3. The absence of transcripts expression exons 2 and 3 was confirmed by RT-PCR on extracts from CD4+CD25- and CD4+CD25+ T cells. (J:144445)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gpr83 Mutation:	23 strains or lines available

Original:	J:144445 Toms C, et al., Gpr83 expression is not required for the maintenance of intestinal immune homeostasis and regulation of T-cell-dependent colitis. Immunology. 2008 Nov;125(3):302-12
All:	3 reference(s)