Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Runx2tm1.1Jals
Name:	runt related transcription factor 2; targeted mutation 1.1, Janet L Stein
MGI ID:	MGI:3829608
Synonyms:	Runx2loxp7
Gene:	Runx2  Location: Chr17:44806873-45125518 bp, - strand  Genetic Position: Chr17, 21.33 cM
Alliance:	Runx2tm1.1Jals page

Germline Transmission:	Earliest citation of germline transmission: J:143532
Parent Cell Line:	AB2.2 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1b-m2

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: Germ line, cre-mediated recombination was used to remove the neo cassette. No expression of truncated transcripts is observed. (J:143532)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Runx2 Mutation:	42 strains or lines available

Original:	J:143532 Lou Y, et al., A Runx2 threshold for the cleidocranial dysplasia phenotype. Hum Mol Genet. 2009 Feb 1;18(3):556-68
All:	1 reference(s)