Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gstt1tm1Kfuj
Name:	glutathione S-transferase, theta 1; targeted mutation 1, Kazunori Fujimoto
MGI ID:	MGI:3828088
Gene:	Gstt1  Location: Chr10:75619647-75634418 bp, - strand  Genetic Position: Chr10, 38.58 cM, cytoband B5-C1
Alliance:	Gstt1tm1Kfuj page

Germline Transmission:	Earliest citation of germline transmission: J:143552
Parent Cell Line:	W9.5/W95 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 1 and 2 were replaced with a neomycin resistance cassette. Mutant ES cell clone 9D5 was used to generate chimeric mice. No mRNA expression coulld be detected in the livers of homozygotes by RT-PCR. (J:143552)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gstt1 Mutation:	14 strains or lines available

Original:	J:143552 Fujimoto K, et al., Generation and functional characterization of mice with a disrupted glutathione S-transferase, theta 1 gene. Drug Metab Dispos. 2007 Dec;35(12):2196-202
All:	1 reference(s)