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Vegfdtm1Hrl
Targeted Allele Detail
Summary
Symbol: Vegfdtm1Hrl
Name: vascular endothelial growth factor D; targeted mutation 1, H R Lijnen
MGI ID: MGI:3826978
Synonyms: VEGF-D-, Vegf-d0
Gene: Vegfd  Location: ChrX:163156374-163185646 bp, + strand  Genetic Position: ChrX, 76.35 cM
Alliance: Vegfdtm1Hrl page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:143070
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2 through 4 were replaced with a lacZ gene and floxed neo cassette. The absence of transcript expression was confirmed by RT-PCR on lung extracts. (J:153734)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Vegfd Mutation:  13 strains or lines available
References
Original:  J:143070 Lijnen HR, et al., Deficiency of vascular endothelial growth factor-D does not affect murine adipose tissue development. Biochem Biophys Res Commun. 2009 Jan 9;378(2):255-8
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory