Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Egfl7tm1.1Cjku
Name:	EGF-like domain 7; targeted mutation 1.1, Calvin J Kuo
MGI ID:	MGI:3826822
Synonyms:	Egfl7delta
Gene:	Egfl7  Location: Chr2:26471095-26482694 bp, + strand  Genetic Position: Chr2, 18.95 cM, cytoband B
Alliance:	Egfl7tm1.1Cjku page

Germline Transmission:	Earliest citation of germline transmission: J:143206
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 5 through 7 were removed by germ line, cre mediated recombination. The absence of transcript expression and presence of Mirn126 transcript expression was confirmed by quantitative PCR on embryo extracts. The absence of protein expression was confirmed by immunohistochemistry of adult tissue. (J:143206)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Egfl7 Mutation:	17 strains or lines available

Original:	J:143206 Kuhnert F, et al., Attribution of vascular phenotypes of the murine Egfl7 locus to the microRNA miR-126. Development. 2008 Dec;135(24):3989-93
All:	1 reference(s)