Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Spint1tm1Bug
Name:	serine protease inhibitor, Kunitz type 1; targeted mutation 1, Thomas H Bugge
MGI ID:	MGI:3822295
Synonyms:	Spint1-
Gene:	Spint1  Location: Chr2:119067841-119079995 bp, + strand  Genetic Position: Chr2, 59.97 cM, cytoband E5
Alliance:	Spint1tm1Bug page

Germline Transmission:	Earliest citation of germline transmission: J:142708
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The coding exons are replaced by a neomycin selection cassette. Absence of mRNA was confirmed by Northern blot analysis. (J:142708)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Spint1 Mutation:	26 strains or lines available

Original:	J:142708 Szabo R, et al., Matriptase inhibition by hepatocyte growth factor activator inhibitor-1 is essential for placental development. Oncogene. 2007 Mar 8;26(11):1546-56
All:	7 reference(s)