Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Spag9tm1Ysok
Name:	sperm associated antigen 9; targeted mutation 1, Katsuji Yoshioka
MGI ID:	MGI:3820229
Synonyms:	Jlptm1Ysok
Gene:	Spag9  Location: Chr11:93886917-94016911 bp, + strand  Genetic Position: Chr11, 58.9 cM, cytoband C
Alliance:	Spag9tm1Ysok page

Germline Transmission:	Earliest citation of germline transmission: J:141755
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A 2.2 kb fragment of genomic DNA including all ox exon 1 was replaced with a neo cassette via homologous recombination. Western blot analysis of testicular cell lysates confirmed the absence of protein in homozygotes. (J:141755)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Spag9 Mutation:	77 strains or lines available

Original:	J:141755 Iwanaga A, et al., Ablation of the scaffold protein JLP causes reduced fertility in male mice. Transgenic Res. 2008 Dec;17(6):1045-58
All:	5 reference(s)