Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Sting1tm1Gnb
Name:	stimulator of interferon response cGAMP interactor 1; targeted mutation 1, Glen N Barber
MGI ID:	MGI:3817418
Synonyms:	Sting-
Gene:	Sting1  Location: Chr18:35866732-35873607 bp, - strand  Genetic Position: Chr18, 19.23 cM, cytoband B3
Alliance:	Sting1tm1Gnb page

Germline Transmission:	Earliest citation of germline transmission: J:141011
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A 4.0 kb region encoding 3 exons and part of a fourth was replaced by a floxed neomycin cassette. Gene inactivation was predicted to be disrupted since the transcriptional start site was included in the deletion region. (J:141011)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sting1 Mutation:	49 strains or lines available

Original:	J:141011 Ishikawa H, et al., STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling. Nature. 2008 Oct 2;455(7213):674-8
All:	76 reference(s)