Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nectin1tm1Mjd
Name:	nectin cell adhesion molecule 1; targeted mutation 1, Michael J Dixon
MGI ID:	MGI:3814719
Gene:	Nectin1  Location: Chr9:43655251-43718758 bp, + strand  Genetic Position: Chr9, 24.42 cM, cytoband B
Alliance:	Nectin1tm1Mjd page

Germline Transmission:	Earliest citation of germline transmission: J:140568
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 1 was replace with a neo cassette. The absence of protein was confirmd by western blot analysis on embryo tissue extracts. (J:140568)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nectin1 Mutation:	22 strains or lines available

Original:	J:140568 Barron MJ, et al., The cell adhesion molecule nectin-1 is critical for normal enamel formation in mice. Hum Mol Genet. 2008 Nov 15;17(22):3509-20
All:	2 reference(s)