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Tex12tm1Hoog
Targeted Allele Detail
Summary
Symbol: Tex12tm1Hoog
Name: testis expressed 12; targeted mutation 1, Christer Hoog
MGI ID: MGI:3811722
Gene: Tex12  Location: Chr9:50468448-50472568 bp, - strand  Genetic Position: Chr9, 27.75 cM
Alliance: Tex12tm1Hoog page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:139993
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2 through 5 were replaced with a floxed neo cassette. The absence of protein was confirmed by western blot analysis. (J:139993)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tex12 Mutation:  6 strains or lines available
References
Original:  J:139993 Hamer G, et al., Progression of meiotic recombination requires structural maturation of the central element of the synaptonemal complex. J Cell Sci. 2008 Aug 1;121(Pt 15):2445-51
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory