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Fem1btm1Mms
Targeted Allele Detail
Summary
Symbol: Fem1btm1Mms
Name: fem 1 homolog b; targeted mutation 1, Michael M Shen
MGI ID: MGI:3811024
Gene: Fem1b  Location: Chr9:62699106-62718930 bp, - strand  Genetic Position: Chr9, 33.87 cM
Alliance: Fem1btm1Mms page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:139640
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsExon 2 was replaced with a floxed neo cassette. The absence of protein expression was confirmed by immunohistochemistry on 14 week testes. (J:139640)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fem1b Mutation:  28 strains or lines available
References
Original:  J:139640 Wang X, et al., Mouse Fem1b interacts with the Nkx3.1 homeoprotein and is required for proper male secondary sexual development. Dev Dyn. 2008 Sep 24;237(10):2963-2972
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory