Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tnfaip8l2tm1Yhcn
Name:	tumor necrosis factor, alpha-induced protein 8-like 2; targeted mutation 1, Youhai H Chen
MGI ID:	MGI:3810526
Synonyms:	TIPE2-
Gene:	Tnfaip8l2  Location: Chr3:95046832-95049671 bp, - strand  Genetic Position: Chr3, 40.74 cM
Alliance:	Tnfaip8l2tm1Yhcn page

Germline Transmission:	Earliest citation of germline transmission: J:139785
Parent Cell Line:	TL1/TL-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: Both exons of this gene locus were replaced by a neomycin resistance cassette. RT-PCR on bone marrow confirmed gene inactivation. (J:139785)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

8 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tnfaip8l2 Mutation:	17 strains or lines available

Original:	J:139785 Sun H, et al., TIPE2, a negative regulator of innate and adaptive immunity that maintains immune homeostasis. Cell. 2008 May 2;133(3):415-26
All:	19 reference(s)