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Crisp1tm1Pasc
Targeted Allele Detail
Summary
Symbol: Crisp1tm1Pasc
Name: cysteine-rich secretory protein 1; targeted mutation 1, Patricia Cuasnicu
MGI ID: MGI:3808726
Gene: Crisp1  Location: Chr17:40604649-40630098 bp, - strand  Genetic Position: Chr17, 19.47 cM
Alliance: Crisp1tm1Pasc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:139154
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 2 was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on epididymal extracts. (J:139154)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 26 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Crisp1 Mutation:  19 strains or lines available
References
Original:  J:139154 Da Ros VG, et al., Impaired sperm fertilizing ability in mice lacking Cysteine-RIch Secretory Protein 1 (CRISP1). Dev Biol. 2008 Aug 1;320(1):12-8
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory