About   Help   FAQ
Ffar2tm1Lex
Targeted Allele Detail
Summary
Symbol: Ffar2tm1Lex
Name: free fatty acid receptor 2; targeted mutation 1, Lexicon Genetics
MGI ID: MGI:3808703
Synonyms: GPR43 KO
Gene: Ffar2  Location: Chr7:30517778-30523200 bp, - strand  Genetic Position: Chr7, 19.25 cM
Alliance: Ffar2tm1Lex page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:138134
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    The exon containing the entire coding region was replaced with a neo selection cassette. (J:138134)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ffar2 Mutation:  25 strains or lines available
References
Original:  J:138134 Ge H, et al., Activation of g protein-coupled receptor 43 in adipocytes leads to inhibition of lipolysis and suppression of plasma free Fatty acids. Endocrinology. 2008 Sep;149(9):4519-26
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory