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Ifit1tm1(KOMP)Vlcg
Targeted Allele Detail
Summary
Symbol: Ifit1tm1(KOMP)Vlcg
Name: interferon-induced protein with tetratricopeptide repeats 1; targeted mutation 1, Velocigene
MGI ID: MGI:3808310
Synonyms: Ifit1tm1Vlcg
Gene: Ifit1  Location: Chr19:34618289-34627409 bp, + strand  Genetic Position: Chr19, 29.78 cM
Alliance: Ifit1tm1(KOMP)Vlcg page
IMPC: Ifit1 gene page
Mutation
origin
Mutant Cell Lines:  10542A-H6, 10542B-B6, 10542B-D8, 10542B-D12, 10542B-H8
Germline Transmission:  Earliest citation of germline transmission: J:187549
Parent Cell Line:  VGB6 (ES Cell)
Strain of Origin:  C57BL/6NTac
Project Collection: KOMP-Regeneron
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: ZEN-Ub1
 
Mutation detailsA lacZ and floxed neo cassette replaced the coding sequence. Western blot analysis confirmed the absence of protein expression in mouse embryonic fibroblasts induced with IFN-beta. (J:136110, J:195382)
Generation of the Ifit1tm1(KOMP)Vlcg allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Ifit1 Mutation:  21 strains or lines available
References
Original:  J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008;
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory