Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Il21rtm1Kopf
Name:	interleukin 21 receptor; targeted mutation 1, Manfred Kopf
MGI ID:	MGI:3800291
Synonyms:	Il-21r-
Gene:	Il21r  Location: Chr7:125202601-125232742 bp, + strand  Genetic Position: Chr7, 68.98 cM, cytoband F4
Alliance:	Il21rtm1Kopf page

Germline Transmission:	Earliest citation of germline transmission: J:137508
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129/Sv

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 2 through 5 were replaced with a neo cassette. The absence of transcript was confirmed by RT-PCR on splenocyte extracts. (J:137508)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Il21r Mutation:	41 strains or lines available

Original:	J:137508 Frohlich A, et al., IL-21 receptor signaling is integral to the development of Th2 effector responses in vivo. Blood. 2007 Mar 1;109(5):2023-31
All:	25 reference(s)