Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Apoftm1(KOMP)Vlcg
Name:	apolipoprotein F; targeted mutation 1, Velocigene
MGI ID:	MGI:3800154
Synonyms:	Apoftm1Vlcg
Gene:	Apof  Location: Chr10:128103866-128106022 bp, + strand  Genetic Position: Chr10, 76.5 cM
Alliance:	Apoftm1(KOMP)Vlcg page
IMPC:	Apof gene page

Mutant Cell Lines:	10417A-D6, 10417A-H2, 10417B-H8
Germline Transmission:	Earliest citation of germline transmission: J:185314
Parent Cell Line:	VGB6 (ES Cell)
Strain of Origin:	C57BL/6NTac
Project Collection:	KOMP-Regeneron

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion     Vector: ZEN-Ub1   Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 1296bp between positions 127705793-127707088 of Chromosome 10 (Genome Build37). The cassette inserted into exon 1. RT-PCR confirmed the absence of transcript expression in the liver. (J:136110)

Generation of the Apoftm1(KOMP)Vlcg allele

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 1 line available
Carrying any Apof Mutation:	14 strains or lines available

Original:	J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008;
All:	3 reference(s)