Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tex11tm1.1Jpt
Name:	testis expressed gene 11; targeted mutation 1.1, John H J Petrini
MGI ID:	MGI:3797590
Synonyms:	Zip4h-
Gene:	Tex11  Location: ChrX:99882254-100103245 bp, - strand  Genetic Position: ChrX, 43.72 cM
Alliance:	Tex11tm1.1Jpt page

Germline Transmission:	Earliest citation of germline transmission: J:136834
Parent Cell Line:	AC1 (ES Cell)
Strain of Origin:	129/Sv

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 3 was deleted by germ line, cre-mediated recombination. Deletion of exon three results in an aberrant splice product with a premature termination condon 6 nucleotides downstream. The absence of full length protein product was confirmed by western blot analysis on P12 testis extracts. A smaller molecular weight protein band was detected at low levels. (J:136834)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tex11 Mutation:	20 strains or lines available

Original:	J:136834 Adelman CA, et al., ZIP4H (TEX11) deficiency in the mouse impairs meiotic double strand break repair and the regulation of crossing over. PLoS Genet. 2008 Mar;4(3):e1000042
All:	1 reference(s)