Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tnfsf15tm1Cdon
Name:	tumor necrosis factor (ligand) superfamily, member 15; targeted mutation 1, Chen Dong
MGI ID:	MGI:3797013
Synonyms:	TL1A-
Gene:	Tnfsf15  Location: Chr4:63642837-63663296 bp, - strand  Genetic Position: Chr4, 34.06 cM
Alliance:	Tnfsf15tm1Cdon page

Germline Transmission:	Earliest citation of germline transmission: J:136280
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129/Sv

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 4 was replaced with neo cassette by targeted homologous recombination. The absence of expression was confirmed by RT-PCR on kidney tissues previously shown to express high levels of the transcripts. This is a null allele. (J:136280)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tnfsf15 Mutation:	19 strains or lines available

Original:	J:136280 Pappu BP, et al., TL1A-DR3 interaction regulates Th17 cell function and Th17-mediated autoimmune disease. J Exp Med. 2008 May 12;205(5):1049-62
All:	3 reference(s)