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Dab2iptm1.1Wami
Targeted Allele Detail
Summary
Symbol: Dab2iptm1.1Wami
Name: disabled 2 interacting protein; targeted mutation 1.1, Wang Min
MGI ID: MGI:3796606
Synonyms: AIP1-
Gene: Dab2ip  Location: Chr2:35448285-35621006 bp, + strand  Genetic Position: Chr2, 23.74 cM
Alliance: Dab2iptm1.1Wami page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:136554
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129 x C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsGerm line, cre-mediated recombination was used to remove exons 5 and 6 as well as the neo cassette. The absence of protein product was confirmed by western blot analysis. (J:136554)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dab2ip Mutation:  56 strains or lines available
References
Original:  J:136554 Luo D, et al., AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response. J Biol Chem. 2008 May 2;283(18):11905-12
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory