Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Fkbp1btm1.1Okam
Name:	FK506 binding protein 1b; targeted mutation 1.1, Hiroshi Okamoto
MGI ID:	MGI:3796254
Gene:	Fkbp1b  Location: Chr12:4883174-4891591 bp, - strand  Genetic Position: Chr12, 2.09 cM
Alliance:	Fkbp1btm1.1Okam page

Germline Transmission:	Earliest citation of germline transmission: J:136192
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129/Sv

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: Germ line, cre-mediated recombination was used to remove the neo cassette and exon 1. The absence of protein product was confirmed by western blot analysis on islet extracts. (J:136192)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fkbp1b Mutation:	14 strains or lines available

Original:	J:136192 Noguchi N, et al., FKBP12.6 disruption impairs glucose-induced insulin secretion. Biochem Biophys Res Commun. 2008 Jul 11;371(4):735-40
All:	1 reference(s)