Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gimap4tm1Jcbs
Name:	GTPase, IMAP family member 4; targeted mutation 1, Heinz Jacobs
MGI ID:	MGI:3795278
Gene:	Gimap4  Location: Chr6:48661483-48668994 bp, + strand  Genetic Position: Chr6, 23.66 cM
Alliance:	Gimap4tm1Jcbs page

Germline Transmission:	Earliest citation of germline transmission: J:135744
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Part of the coding region in exon 3 was replaced with a floxed neo cassette. Germ line, cre mediated recombination was used to remove the neo cassette. The absence of protein produce was confirmed by western blot analysis on lymphocyte extracts. (J:135744)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gimap4 Mutation:	21 strains or lines available

Original:	J:135744 Schnell S, et al., Gimap4 accelerates T-cell death. Blood. 2006 Jul 15;108(2):591-9
All:	1 reference(s)