Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Serpina10tm1Gjb
Name:	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10; targeted mutation 1, George J Broze
MGI ID:	MGI:3795215
Synonyms:	ZPI-
Gene:	Serpina10  Location: Chr12:103582934-103597681 bp, - strand  Genetic Position: Chr12, 52.97 cM
Alliance:	Serpina10tm1Gjb page

Germline Transmission:	Earliest citation of germline transmission: J:136102
Parent Cell Line:	RW-4 (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Part of exon 2 was replaced with a neo cassette. The absence of protein product was confirmed by western blot analysis on mouse plasma extracts. (J:136102)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Serpina10 Mutation:	23 strains or lines available

Original:	J:136102 Zhang J, et al., Protein Z-dependent protease inhibitor deficiency produces a more severe murine phenotype than protein Z deficiency. Blood. 2008 May 15;111(10):4973-8
All:	3 reference(s)