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Mcm3aptm2Imku
Targeted Allele Detail
Summary
Symbol: Mcm3aptm2Imku
Name: minichromosome maintenance complex component 3 associated protein; targeted mutation 2, Nobuo Sakaguchi
MGI ID: MGI:3794112
Synonyms: ganpd
Gene: Mcm3ap  Location: Chr10:76304761-76351691 bp, + strand  Genetic Position: Chr10, 38.88 cM
Alliance: Mcm3aptm2Imku page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:135369
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exon 1 and part of exon 2 containing the initiation methionine was replaced with a neo cassette. (J:135369)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mcm3ap Mutation:  77 strains or lines available
References
Original:  J:135369 Yoshida M, et al., GANP suppresses DNA recombination, measured by direct-repeat beta-galactosidase gene construct, but does not suppress the type of recombination applying to immunoglobulin genes in mammalian cells. Genes Cells. 2007 Oct;12(10):1205-13
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory