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Krtap10-25 Gene Detail
Summary
  • Symbol
    Krtap10-25
  • Name
    keratin associated protein 10-25
  • Synonyms
    Gm7137
  • Feature Type
    protein coding gene
  • IDs
    MGI:3779677
    NCBI Gene: 634504
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:77623324-77624034 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • Strain Annotations
    7
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3779677
 protein coding gene Chr10:77623256-77624034 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J MGP_AKRJ_G0017346
 protein coding gene Chr10:77422910-77423812 (-)
BALB/cJ MGP_BALBcJ_G0017346
 protein coding gene Chr10:75609709-75610321 (-)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0017803
 protein coding gene Chr10:80869670-80870882 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J MGP_DBA2J_G0017246
 protein coding gene Chr10:74663159-74678185 (-)
FVB/NJ MGP_FVBNJ_G0017239
 protein coding gene Chr10:73845393-73846301 (-)
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0017843
 protein coding gene Chr10:77480452-77507548 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    KRTAP10-10, keratin associated protein 10-10
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRTAP10-10, keratin associated protein 10-10
  • Synonyms
    KAP10.10, KAP18.10, KRTAP18-10, KRTAP18.10
  • Links
    NCBI Gene ID: 353333
    neXtProt AC: NX_P60014
    UniProt: P60014

  • Chr Location
    21q22.3; chr21:44637356-44638455 (+)  GRCh38
  • Human Ortholog
    KRTAP10-3, keratin associated protein 10-3
  • Synonyms
    KAP10.3, KAP18-3, KAP18.3, KRTAP10.3, KRTAP18-3, KRTAP18.3
  • Links
    NCBI Gene ID: 386682
    neXtProt AC: NX_P60369
    UniProt: P60369

  • Chr Location
    21q22.3; chr21:44557790-44558795 (-)  GRCh38
  • Human Ortholog
    KRTAP10-7, keratin associated protein 10-7
  • Synonyms
    KAP10.7, KAP18.7, KRTAP18-7
  • Links
    NCBI Gene ID: 386675
    neXtProt AC: NX_P60409
    UniProt: P60409

  • Chr Location
    21q22.3; chr21:44600597-44602174 (+)  GRCh38
Human Diseases
less
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    26 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Targeted
    3
  • Genomic Mutations
    4 involving Krtap10-25
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    4 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
  • All Sequences
    14
  • RefSeq
    2
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000095721 Ensembl Gene Model | MGI Sequence Detail 711 C57BL/6J ±  kb
transcript ENSMUST00000180161 Ensembl | MGI Sequence Detail 711 Not Applicable  
polypeptide ENSMUSP00000136480 Ensembl | MGI Sequence Detail 236 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR002494 Keratin-associated protein
References
more
  • Summaries
    All 33
    Diseases 2
    Gene Ontology 1
    Phenotypes 26
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:341136 Muza PM, et al., Cognitive impairments in a Down syndrome model with abnormal hippocampal and prefrontal dynamics and cytoarchitecture. iScience. 2023 Feb 17;26(2):106073
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory