Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Prkd1tm1.1Eno
Name:	protein kinase D1; targeted mutation 1.1, Eric N Olson
MGI ID:	MGI:3778382
Synonyms:	PKD1-
Gene:	Prkd1  Location: Chr12:50388014-50695881 bp, - strand  Genetic Position: Chr12, 21.78 cM, cytoband C1
Alliance:	Prkd1tm1.1Eno page

Germline Transmission:	Earliest citation of germline transmission: J:132803
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S/SvEv

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: Prkd1tm1Eno mice were crossed with a mouse strain where cre recombinase is expressed in the germline. This removed the segments of the gene that encode for kinase activity and was predicted to generate a null allele. (J:132803)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prkd1 Mutation:	55 strains or lines available

Original:	J:132803 Fielitz J, et al., Requirement of protein kinase D1 for pathological cardiac remodeling. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):3059-63
All:	1 reference(s)