Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Slc51atm1Pda
Name:	solute carrier family 51, alpha subunit; targeted mutation 1, Paul A Dawson
MGI ID:	MGI:3778302
Gene:	Slc51a  Location: Chr16:32294396-32306697 bp, - strand  Genetic Position: Chr16, 22.7 cM
Alliance:	Slc51atm1Pda page

Germline Transmission:	Earliest citation of germline transmission: J:132778
Parent Cell Line:	SM1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 1 and 2 were replaced with a neo cassette. The absence of protein product was confirmed by western blot analysis on ileal extracts. (J:132778)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slc51a Mutation:	21 strains or lines available

Original:	J:132778 Rao A, et al., The organic solute transporter alpha-beta, Ostalpha-Ostbeta, is essential for intestinal bile acid transport and homeostasis. Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3891-6
All:	5 reference(s)