Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Zbp1tm1Aki
Name:	Z-DNA binding protein 1; targeted mutation 1, Shizuo Akira
MGI ID:	MGI:3776827
Synonyms:	DAI-
Gene:	Zbp1  Location: Chr2:173048405-173060715 bp, - strand  Genetic Position: Chr2, 95.83 cM, cytoband H3
Alliance:	Zbp1tm1Aki page

Germline Transmission:	Earliest citation of germline transmission: J:132662
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Part of exon 2 and all of exon 3 were replaced with a neomycin resistance cassette. A lack of gene expression was confirmed by northern blot analysis of embryonic fibroblasts isolated from homozygotes. (J:132662)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Zbp1 Mutation:	28 strains or lines available

Original:	J:132662 Ishii KJ, et al., TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines. Nature. 2008 Feb 7;451(7179):725-9
All:	30 reference(s)