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Cerktm1Fbor
Targeted Allele Detail
Summary
Symbol: Cerktm1Fbor
Name: ceramide kinase; targeted mutation 1, Frederic Bornancin
MGI ID: MGI:3774547
Gene: Cerk  Location: Chr15:86023329-86070342 bp, - strand  Genetic Position: Chr15, 40.52 cM
Alliance: Cerktm1Fbor page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:131522
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  BALB/c
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2 through 5 were replaced with a floxed neo cassette. The lack of transcript expression was confirmed by real-time PCR. (J:131522)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cerk Mutation:  24 strains or lines available
References
Original:  J:131522 Graf C, et al., Neutropenia with Impaired Immune Response to Streptococcus pneumoniae in Ceramide Kinase-Deficient Mice. J Immunol. 2008 Mar 1;180(5):3457-66
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory