Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Trim63tm1Slbt
Name:	tripartite motif-containing 63; targeted mutation 1, Siegfried Labeit
MGI ID:	MGI:3773034
Synonyms:	MuRF1 KO
Gene:	Trim63  Location: Chr4:134042431-134056940 bp, + strand  Genetic Position: Chr4, 66.58 cM
Alliance:	Trim63tm1Slbt page

Germline Transmission:	Earliest citation of germline transmission: J:130921
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Most of exon 2 was replaced with a neo cassette with stop codons in all three reading frames. The absence of transcript was confirmed by RT-PCR. (J:130921)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Trim63 Mutation:	18 strains or lines available

Original:	J:130921 Witt CC, et al., Cooperative control of striated muscle mass and metabolism by MuRF1 and MuRF2. EMBO J. 2008 Jan 23;27(2):350-60
All:	5 reference(s)