Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Casp14tm1Wdec
Name:	caspase 14; targeted mutation 1, Wim Declercq
MGI ID:	MGI:3770173
Synonyms:	Casp14-, caspase-14-
Gene:	Casp14  Location: Chr10:78547825-78554128 bp, - strand  Genetic Position: Chr10, 39.72 cM, cytoband C1
Alliance:	Casp14tm1Wdec page

Germline Transmission:	Earliest citation of germline transmission: J:129490
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 3 and 4 were replaced with a neo cassette to create a null allele. The absence of protein product was confirmed by western blot analysis. (J:129490)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Casp14 Mutation:	13 strains or lines available

Original:	J:129490 Denecker G, et al., Caspase-14 protects against epidermal UVB photodamage and water loss. Nat Cell Biol. 2007 Jun;9(6):666-74
All:	7 reference(s)