Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Scn1btm2.1Isom
Name:	sodium channel, voltage-gated, type I, beta; targeted mutation 2.1, Lori L Isom
MGI ID:	MGI:3768514
Synonyms:	Scn1bdel
Gene:	Scn1b  Location: Chr7:30815949-30826428 bp, - strand  Genetic Position: Chr7, 19.3 cM
Alliance:	Scn1btm2.1Isom page

Germline Transmission:	Earliest citation of germline transmission: J:128713
Parent Cell Line:	Pat5 (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: Scn1btm2Isom mice were mated with transgenic mice that ubiquitously express Cre to remove the floxed allele. Gene inactivation was demonstrated by western blot and by in situ hybridization of brain tissue. (J:128713)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Scn1b Mutation:	6 strains or lines available

Original:	J:128713 Chen C, et al., Floxed allele for conditional inactivation of the voltage-gated sodium channel beta1 subunit Scn1b. Genesis. 2007 Sep;45(9):547-53
All:	1 reference(s)