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Jsrp1tm1Zor
Targeted Allele Detail
Summary
Symbol: Jsrp1tm1Zor
Name: junctional sarcoplasmic reticulum protein 1; targeted mutation 1, Francesco Zorzato
MGI ID: MGI:3768247
Gene: Jsrp1  Location: Chr10:80644330-80649332 bp, - strand  Genetic Position: Chr10, 39.72 cM, cytoband C1
Alliance: Jsrp1tm1Zor page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:128603
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 3 and its upstream intron were replaced with a neo cassette. The absence of protein product was confirmed by western blot analysis on sacroplasmic reticulum fraction of skeletal muscle protein extracts. (J:128603)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Jsrp1 Mutation:  13 strains or lines available
References
Original:  J:128603 Delbono O, et al., Loss of skeletal muscle strength by ablation of the sarcoplasmic reticulum protein JP45. Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):20108-13
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory