Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Akap5tm2Gsm
Name:	A kinase anchor protein 5; targeted mutation 2, G Stanley Mcknight
MGI ID:	MGI:3766311
Synonyms:	AKAP150 -
Gene:	Akap5  Location: Chr12:76371665-76380927 bp, + strand  Genetic Position: Chr12, 33.73 cM
Alliance:	Akap5tm2Gsm page

Germline Transmission:	Earliest citation of germline transmission: J:128208
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The entire coding region of the gene was replaced with a neomycin phosphotransferase cassette. Immunoblotting of forebrain lysates from homozgyote mice confirmed gene inactivation. (J:128208, J:160134)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Akap5 Mutation:	27 strains or lines available

Original:	J:128208 Hall DD, et al., Critical role of cAMP-dependent protein kinase anchoring to the L-type calcium channel Cav1.2 via A-kinase anchor protein 150 in neurons. Biochemistry. 2007 Feb 13;46(6):1635-46
All:	17 reference(s)