Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tead4tm1.1Bnno
Name:	TEA domain family member 4; targeted mutation 1.1, Andres Buonanno
MGI ID:	MGI:3763362
Synonyms:	Tead4-, Teadtm
Gene:	Tead4  Location: Chr6:128204106-128277776 bp, - strand  Genetic Position: Chr6, 62.92 cM
Alliance:	Tead4tm1.1Bnno page

Germline Transmission:	Earliest citation of germline transmission: J:126338
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: Exon 2 was removed by cre-mediated recombination. This exon codes for the TEA DNA-binding domain. Absence of transcript in all normally expressing tissues was confirmed by RT-PCR. (J:126338)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	40 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tead4 Mutation:	75 strains or lines available

Original:	J:126338 Yagi R, et al., Transcription factor TEAD4 specifies the trophectoderm lineage at the beginning of mammalian development. Development. 2007 Nov;134(21):3827-36
All:	4 reference(s)